May 17, 2011Nephrology Dialysis Transplantation

High normal levels of albuminuria and risk of hypertension in Indo-Asian population

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Why the study?

Does high normal albuminuria predict incident hypertension in normotensive non-diabetic Indo-Asian adults?

Structured PICO

Does high normal albuminuria predict incident hypertension in normotensive non-diabetic Indo-Asian adults?

Population

1272 normotensive non-diabetic adults aged ≥ 40 years with UACR <30 mg/g in Pakistan

Intervention

High normal levels of albuminuria (UACR top quartile ≥ 6.1 mg/g and third quartile 3.8-6.1 mg/g)

Comparator

Low normal levels of albuminuria (UACR lowest quartile <2.8 mg/g)

Outcome

Incident hypertension (new onset of systolic blood pressure ≥ 140 mmHg or diastolic ≥ 90 mmHg or initiation of antihypertensive therapy) at 2-year follow-upsurrogate

High normal levels of albuminuria predict the development of incident hypertension in non-diabetic Indo-Asian adults, particularly those with lower baseline systolic blood pressure.

Discussion

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Implication

May flag at-risk Indo-Asians for closer BP monitoring; extends prior data but leaves open prospective validation.

Cite This Study

Jessani et al. (2011) studied this question.

synapsesocial.com/papers/6a85cc171900a0910e86cb26 https://doi.org/10.1093/ndt/gfr200

Topics

Hypertension management

View Full Paper

Ask AI

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High normal levels of albuminuria and risk of hypertension in Indo-Asian population

Structured PICO

Discussion

Implication

Cite This Study

Topics

High normal levels of albuminuria and risk of hypertension in Indo-Asian population

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider