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January 20, 2016Clinical Journal of the American Society of Nephrology

Structural Predictors of Loss of Renal Function in American Indians with Type 2 Diabetes

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Population

111 American Indians with type 2 diabetes who volunteered for a research kidney biopsy at the end of a…

Design

Cohort

Follow-up

median 6.6 years

Authors

GFGudeta D. FufaaEWE. Jennifer WeilKLKevin V. Lemley

Discussion

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Overview

Does not support routine biopsy-based risk stratification; leaves open whether glomerular morphometry improves prediction beyond clinical factors in diabetes.

Structured PICO

P
Population
111 American Indians with type 2 diabetes who volunteered for a research kidney biopsy at the end of a 6-year clinical trial, mean age 46 years, 82% women.
O
Outcome
Renal function loss defined as ≥40% loss of GFR from the research examination performed at the time of kidney biopsysurrogate

Quantitative measures of glomerular structure predict loss of renal function in American Indians with type 2 diabetes.

Cite This Study

Fufaa et al. (2016) studied this question.

synapsesocial.com/papers/6a8651aee3ff5bf5642ecdd8https://doi.org/10.2215/cjn.05760515
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