January 1, 1989The Journal of PhysiologyOpen Access

A dynamic analysis of the ventilatory response to hypoxia in man.

View Full Paper

Ask AI

Bookmark

Population

7 healthy subjects

Design

Other

Authors

JBJ.F. BertholonSorbonne Université MEMaguy EugèneUnité Mixte de Recherche sur les Herbivores ELE LabeyrieHôpital Joseph-Ducuing

Discussion

Member takes

Implication

No immediate clinical implications for hypoxia management; leaves open discrete excitatory states in central ventilatory control.

Structured PICO

Population

7 healthy subjects

Intervention

Isocapnic hypoxia at four different levels (inspired oxygen pressures 110, 100, 80, and 60 mmHg) successively increasing and decreasing stepwise for varying durations

Outcome

Ventilatory response curves (PA,O2-VE) including loop surface area, magnitude of response to rising hypoxic steps, and difference between resting VE and VE at PA,O2 50 mmHgsurrogate

The dynamics of the ventilatory response to hypoxia suggest the existence of discrete excitatory states of the central neural controller.

Cite This Study

Bertholon et al. (1989) studied this question.

synapsesocial.com/papers/6a86526b894d3eb3a35aee4d https://doi.org/10.1113/jphysiol.1989.sp017471

View Full Paper

Ask AI

Bookmark

A dynamic analysis of the ventilatory response to hypoxia in man.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

A dynamic analysis of the ventilatory response to hypoxia in man.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider