May 1, 1976Circulation ResearchOpen Access

Altered venous function in hypertensive rats.

View Full Paper

Ask AI

Bookmark

Population

Hypertensive rats including genetically hypertensive rats, spontaneously hypertensive rats, two-kidney…

Comparison

Measurement of venous pressure-volume curves via… vs Weight- and sex-matched normotensive control rats.

Design

Preclinical

Authors

GSG. SimónInstitut Lumière Matière

Discussion

Member takes

Implication

Altered venous capacity in hypertensive rat models merits human studies; leaves open its role in clinical hypertension.

Structured PICO

Population

Hypertensive rats including genetically hypertensive rats (GHR, n=13), spontaneously hypertensive rats (SHR, n=8), two-kidney Goldblatt hypertension (2-KGH, n=12), and one-kidney Goldblatt hypertension (1-KGH, n=8), along with weight- and sex-matched normotensive controls.

Intervention

Measurement of venous pressure-volume curves via rapid infusion of Krebs-Ringer solution into the inferior vena cava.

Comparator

Weight- and sex-matched normotensive control rats.

Outcome

Venous pressure-volume curves (venous capacity).surrogate

Hypertensive rat models exhibit decreased venous capacity, suggesting altered venous function in hypertension.

Cite This Study

G. Simón (1976) studied this question.

synapsesocial.com/papers/6a865d55e7c8470ab14ca9fc https://doi.org/10.1161/01.res.38.5.412

Topics

Hypertension management

View Full Paper

Ask AI

Bookmark

Altered venous function in hypertensive rats.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Altered venous function in hypertensive rats.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider