Why the study?
Does a modified catheter with a surgical blade create lacerations in the atrial septum in animal and in vitro models?
Population
Five newborn lambs in vivo, and adult dog hearts and human hearts in vitro
Design
Preclinical
Authors
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Preclinical blade septostomy feasible in animals; leaves open translation to human septal interventions.
Does a modified catheter with a surgical blade create lacerations in the atrial septum in animal and in vitro models?
A novel catheter-based surgical blade technique successfully created 8-12 mm lacerations in the atrial septum in preclinical models, offering a potential alternative when balloon septostomy is ineffective.
Park et al. (1975) studied this question.
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