February 1, 2007Obstetrics and Gynecology

Nuchal Translucency and the Risk of Congenital Heart Disease

View Full Paper

Ask AI

Bookmark

Why the study?

Does nuchal translucency sonography accurately screen for major congenital heart disease in unselected euploid fetuses?

Population

34,266 unselected patients with singleton pregnancies at 10 to 13 weeks of gestation with euploid fetuses…

Design

Cohort

Authors

LSLynn L. SimpsonNewYork–Presbyterian Hospital FMFergal D. MaloneRoyal College of Surgeons in Ireland DBDiana W. BianchiNational Human Genome Research Institute

Discussion

Member takes

Implication

May support targeted echocardiography referral for NT ≥2.5 MoM; leaves open its role in general major CHD screening.

Structured PICO

Does nuchal translucency sonography accurately screen for major congenital heart disease in unselected euploid fetuses?

Population

34,266 unselected patients with singleton pregnancies at 10(3/7) to 13(6/7) weeks of gestation with euploid fetuses, recruited at 15 U.S. centers.

Intervention

Nuchal translucency sonography assessment (evaluated at cutoffs of ≥2.0, ≥2.5, and ≥3.0 multiples of the median [MoM]).

Outcome

Detection of major congenital heart disease (CHD).surrogate

While nuchal translucency lacks the characteristics of a good general screening tool for major CHD, a measurement of ≥2.5 MoM (≥99th percentile) warrants referral for fetal echocardiography.

Cite This Study

Simpson et al. (2007) studied this question.

synapsesocial.com/papers/6a86683356d979df551b2e8a https://doi.org/10.1097/01.aog.0000250473.99575.72

Topics

Congenital heart disease adults

View Full Paper

Ask AI

Bookmark

Nuchal Translucency and the Risk of Congenital Heart Disease

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Nuchal Translucency and the Risk of Congenital Heart Disease

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider