Why the study?
Does total IV anesthesia compared to balanced anesthesia reduce intraoperative stress and sympathetic outflow in patients undergoing ear-nose-throat surgery?
Does total IV anesthesia compared to balanced anesthesia reduce intraoperative stress and sympathetic outflow in patients undergoing ear-nose-throat surgery?
Total intravenous anesthesia with propofol/remifentanil attenuates intraoperative sympathetic outflow and stress hormone release compared to balanced anesthesia with sevoflurane/remifentanil during ear-nose-throat surgery.
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TIVA may be preferred to blunt sympathetic activation in ENT surgery; extends RCT evidence on anesthetic effects on stress hormones.
Ledowski et al. (2005) studied this question.
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