Key result
Balanced anaesthesia with sevoflurane compared to isoflurane resulted in similar variations of haemodynamic variables and heart rate variability parameters, with no statistically significant differences between the groups.
Why the study?
Does sevoflurane compared to isoflurane alter heart rate variability in patients undergoing elective abdominal surgery?
Population
64 patients of ASA I and ASA II status scheduled for elective abdominal surgical procedures
Comparison
Balanced anaesthesia with sevoflurane (n=32) vs Balanced anaesthesia with isoflurane (n=32)
Design
RCT, randomly allocated
Follow-up
perioperative period
Authors
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Supports interchangeable use of either agent by availability or preference; confirms comparable autonomic effects during balanced anaesthesia for abdominal surgery.
RCT (n=64)
Randomly allocated
No
Does sevoflurane compared to isoflurane alter heart rate variability in patients undergoing elective abdominal surgery?
p-value: p=>0.05
Sevoflurane and isoflurane have comparable effects on heart rate variability and haemodynamic parameters during balanced anaesthesia for abdominal surgery.
Meldijana Omerbegovi (2014) conducted an RCT in ASA I and ASA II status scheduled for elective abdominal surgical procedures (n=64). Sevoflurane vs. Isoflurane was evaluated on Heart rate variability parameters (TP, LF, HF, SD1, SD2) and haemodynamic variables (p=>0.05). Balanced anaesthesia with sevoflurane compared to isoflurane resulted in similar variations of haemodynamic variables and heart rate variability parameters, with no statistically significant differences between the groups.
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