Why the study?
What are the long-term survival and structural deterioration rates of the Ionescu-Shiley Low-Profile bioprosthetic heart valve in adults?
Population
708 adults with isolated aortic or mitral Ionescu-Shiley Low-Profile pericardial valves
Design
Cohort
Follow-up
mean 6.7 years
Authors
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Higher mitral deterioration rates support enhanced post-MVR surveillance; leaves open durability comparisons across bioprostheses.
What are the long-term survival and structural deterioration rates of the Ionescu-Shiley Low-Profile bioprosthetic heart valve in adults?
The ISLP bioprosthetic valve shows increasing structural deterioration after 7 years, requiring regular surveillance and consideration of long-term anticoagulation due to higher than expected thrombo-embolic events.
Wheatley et al. (1994) studied this question.
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