Population
Cultured cardiomyocytes and monocrotaline-induced pulmonary hypertension in vivo model of right ventricular…
Comparison
Electrical stimulation, higher oxygen content… vs Control conditions
Design
Preclinical
Authors
Loading...
May link glycolysis to ET-1 via HIF-1α in cardiomyocytes; leaves open translation to human cardiac disease or therapy.
Enhanced glycolysis in cardiomyocytes regulates the expression of endothelin-1 via the transcription factor HIF-1 alpha, linking cardiac energy metabolism to gene expression.
Kakinuma et al. (2002) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: