Why the study?
Geriatric hip fracture patients on clopidogrel often face surgical delay of 5 to 7 days after withdrawal, which increases complications and mortality.
Does early surgery within 5 days of clopidogrel withdrawal increase perioperative blood loss in geriatric hip fracture patients compared to those not taking antiplatelet drugs?
Population
120 acute hip fracture patients (≥65 years) in Beijing, China
Comparison
Surgery <5 days after clopidogrel withdrawal vs no antiplatelet or anticoagulant drugs
Design
Retrospective matched case-control study
Follow-up
1-year
Authors
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May support earlier hip fracture surgery after clopidogrel; leaves open need for randomized trials before practice change.
Does early surgery within 5 days of clopidogrel withdrawal increase perioperative blood loss in geriatric hip fracture patients compared to those not taking antiplatelet drugs?
Early hip fracture surgery within 5 days of clopidogrel withdrawal appears safe and does not significantly increase overall perioperative blood loss or mortality compared to patients not on antiplatelet therapy.
Yang et al. (2021) studied this question.
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