Why the study?
Does clopidogrel or other oral anticoagulants increase bleeding complications or mortality in patients ≥60 years undergoing early hip fracture surgery?
Population
1,036 patients ≥60 years of age undergoing early surgical treatment for a hip fracture.
Comparison
Clopidogrel (alone or in combination with aspirin) vs Aspirin alone, warfarin alone, or no…
Design
Cohort
Follow-up
up to 1 year
Authors
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No increased bleeding or mortality observed with clopidogrel during early hip fracture repair; leaves open need for randomized confirmation before changing practice.
Does clopidogrel or other oral anticoagulants increase bleeding complications or mortality in patients ≥60 years undergoing early hip fracture surgery?
Early hip fracture surgery can be safely performed in older patients taking clopidogrel, aspirin, or warfarin without a substantially increased risk of bleeding complications or mortality.
Collinge et al. (2012) studied this question.
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