Why the study?
Does clopidogrel use increase transfusion requirements or complications in patients undergoing nonelective orthopaedic surgery?
Population
61 patients requiring nonelective orthopaedic surgery from 2004 to 2008.
Comparison
Clopidogrel use prior to surgery vs Matched control group not taking clopidogrel
Design
Cohort
Follow-up
30 days
Authors
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No excess transfusion or complications seen with clopidogrel; leaves open perioperative continuation pending randomized confirmation.
Does clopidogrel use increase transfusion requirements or complications in patients undergoing nonelective orthopaedic surgery?
Continuing clopidogrel without surgical delay in patients requiring nonelective orthopaedic surgery appears safe, without significantly increasing transfusion requirements or complications.
Nydick et al. (2010) studied this question.
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