Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
October 19, 1940JAMAOpen Access

Tobacco and Coronary Disease

View Full Paper
Ask AI
Bookmark
Share

Authors

JEJOHN P. ENGLISHFWFredrick A. WilliusMayo Clinic

Discussion

Loading...

Member takes

Implication

Observational analysis reveals reduced life expectancy among tobacco smokers compared with nonsmokers, highlighting the clinical risks of tobacco in coronary disease.

Key Points

  • To examine the physiological effects of tobacco smoking on human health, longevity, and coronary disease relative to laboratory animal models.
  • Reviewed laboratory animal experiments evaluating physiological responses to tobacco smoke inhalation.
  • Evaluated human epidemiological and actuarial records, specifically analyzing Pearl's study of human longevity among smokers versus nonsmokers.
  • Animal laboratory studies fail to replicate the complex conditions and multigenerational exposure patterns present in human populations.
  • Human life expectancy for nonsmokers significantly exceeds that of smokers, with higher mortality observed among tobacco users.

Cite This Study

ENGLISH et al. (1940) studied this question.

synapsesocial.com/papers/6a86922105076cf37f2d78f2https://doi.org/10.1001/jama.1940.02810420013004
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Smoking‐Related Morbidity and Mortality in the Cardiovascular Setting2007 · 58 citations
  2. 2CHARACTERISTICS OF SMOKERS COMPARED WITH NONSMOKERS IN A POPULATION OF HEALTHY YOUNG ADULTS, INCLUDING OBSERVATIONS ON FAMILY HISTORY, BLOOD PRESSURE, HEART RATE, BODY WEIGHT, CHOLESTEROL AND CERTAIN PSYCHOLOGIC TRAITS1960 · 61 citations
  3. 3Effect of Smoking on the Cardiovascular System of Man1958 · 59 citations
  4. 4Total life consumption of cigarettes as a determinant of coronary artery disease documented by coronary arteriography2005
  5. 5Biochemical evidence of persistent heavy smoking after a coronary diagnosis despite self-reported reduction: analysis from the Scottish Heart Health Study1992 · 54 citations