Why the study?
Does routine screening for coagulation inhibitors prior to prescribing oral contraceptives accurately identify deficiencies in healthy women?
Population
2,674 apparently healthy women who are candidates for oral contraceptives
Design
Cross-sectional
Authors
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High false-positive rates compromise routine inhibitor screening before oral contraceptives; leaves open targeted testing in high-risk subgroups.
Does routine screening for coagulation inhibitors prior to prescribing oral contraceptives accurately identify deficiencies in healthy women?
Unselected routine screening for coagulation inhibitors before prescribing oral contraceptives yields a high rate of false positives and is not recommended, except possibly for those with a family history of thromboembolic disease.
Winkler et al. (1996) studied this question.
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