Key result
Oral contraceptive use in women was associated with significantly lower total protein S levels (24.3 vs 28.6 micrograms/mL; P<0.005) compared to women not taking oral contraceptives.
Why the study?
Does oral contraceptive use reduce protein S levels in women?
Population
63 individuals, comprising 21 women taking oral contraceptives, 21 women not taking oral contraceptives, and…
Comparison
Oral contraceptive use vs No oral contraceptive use (in women)
Design
Cross-sectional
Authors
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OC use may elevate thrombotic risk via lower protein S; hypothesis-generating in cross-sectional data.
Cross-Sectional (n=63)
Does oral contraceptive use reduce protein S levels in women?
Absolute Event Rate: 24.3% vs 28.6%
p-value: p=<.005
Oral contraceptive use and female gender are associated with lower levels of protein S, which may contribute to an increased risk of thrombotic complications.
Boerger et al. (1987) reported a cross-sectional. Oral contraceptives vs. Women not taking oral contraceptives was evaluated on Total protein S levels (p=<.005). Oral contraceptive use in women was associated with significantly lower total protein S levels (24.3 vs 28.6 micrograms/mL; P<0.005) compared to women not taking oral contraceptives.
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