This case highlights the imaging and histologic presentation of a rare cystic retroperitoneal dedifferentiated liposarcoma in an elderly patient.
Alerts clinicians to atypical cystic liposarcoma on imaging; extends differential for retroperitoneal masses but leaves open validation needs.
Liposarcoma is the most common primary retroperitoneal sarcoma in adults. We report the case of an 86-year-old male who presented to the emergency department with frequent falls and unexplained weight loss that was found to have a cystic retroperitoneal dedifferentiated liposarcoma. Initial computed tomography revealed a large heterogeneous complex cystic hypoenhancing lesion in the left retroperitoneum. Subsequent magnetic resonance imaging demonstrates a multilocular cystic mass with microscopic lipid content, diffusion restriction, and enhancing nodular soft-tissue components. Histologic examination of the tissue sample following biopsy is consistent with cystic retroperitoneal dedifferentiated liposarcoma. Further management was not pursued due to the patient's advanced age and frailty.
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Sorour et al. (2023) studied this question.
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