Why the study?
Traditional Chinese medicines have shown good outcomes in chronic heart failure, prompting investigation into the therapeutic effect of Shen Qi Li Xin formula.
Does Shen Qi Li Xin formula improve cardiac function and hemodynamics in a rat model of chronic heart failure?
Population
CHF rats and primary pericytes
Comparison
SQLXF at 8.48, 16.96, and 33.92 g/kg/d vs normal rats
Design
Preclinical in vivo and in vitro study
Follow-up
4 weeks
Authors
Loading...
Animal findings on SQLXF in rat CHF warrant no clinical change; leaves open need for human trials.
Does Shen Qi Li Xin formula improve cardiac function and hemodynamics in a rat model of chronic heart failure?
Shen Qi Li Xin formula improves cardiac function and attenuates myocardial injury in a rat model of chronic heart failure, potentially by enhancing pericyte-endothelial cell interactions.
Sui et al. (2022) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: