Why the study?
Does the -265T/C polymorphism in the apoA-II gene affect visceral fat accumulation and triglyceride-rich lipoprotein metabolism in healthy men?
Does the -265T/C polymorphism in the apoA-II gene affect visceral fat accumulation and triglyceride-rich lipoprotein metabolism in healthy men?
A functional polymorphism (-265T/C) in the apoA-II gene provides evidence that apoA-II promotes visceral fat accumulation and impairs the metabolism of large VLDLs in humans.
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Supports apoA-II in visceral fat and VLDL metabolism; hypothesis-generating and should not change practice.
Ruotolo et al. (2001) studied this question.
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