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August 20, 2026Cardiology DiscoveryOpen Access

Pulmonary Artery Aneurysms Diagnosed in Hospitalizations in the United States and the In-Hospital Outcomes: Insights From the National Inpatient Sample

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Authors

CKChun Shing KwokGBGagan BhambraBSBharat Sidhu

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Overview

Observational cohort study reveals high in-hospital mortality and healthcare costs among hospitalized patients with pulmonary artery aneurysms, highlighting the impact of severe comorbidities.

Key Points

  • To determine the diagnosis incidence, clinical outcomes, and predictors of in-hospital mortality among hospitalized patients with pulmonary artery aneurysms in the United States.
  • Retrospective observational cohort study analyzing the US National Inpatient Sample (2016–2020) for adult admissions with ICD-10 diagnosis of pulmonary artery aneurysm (N=5,305).
  • Applied backward stepwise multivariable logistic regression for in-hospital mortality and backward stepwise linear regression for length of stay and total hospital charges.
  • In-hospital mortality was 6.7% (355/5,305), with a median length of stay of 5 days and a median hospital cost of $17,526.
  • Independent predictors of in-hospital mortality included tuberculosis (OR: 22.67, 95% CI: 3.35–153.32, P=0.001), liver failure (OR: 15.91, 95% CI: 6.31–40.09, P<0.001), and Eisenmenger syndrome (OR: 12.05, 95% CI: 1.06–136.42, P=0.044).
  • Prolonged hospital stay was most strongly associated with liver failure (coefficient: 17.84, 95% CI: 12.99–22.67, P<0.001), while iatrogenic complications were the largest driver of increased hospital costs (coefficient: $64,590, 95% CI: 35,308–93,872, P<0.001).

Cite This Study

Kwok et al. (2026) studied this question.

synapsesocial.com/papers/6a86b56c8a91293e6a1cccc6https://doi.org/10.1097/cd9.0000000000000200
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Also Consider

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