Key result
Long-term amiodarone therapy in a 77-year-old man caused multi-system toxicity, specifically amiodarone-induced thyrotoxicosis and steatohepatitis.
Why the study?
Amiodarone accumulates in several organs, with increasing reports of adverse events affecting the lungs, liver, thyroid gland, eyes, skin, and nervous system.
Case Report (n=1)
No
Long-term amiodarone therapy can cause simultaneous multisystem toxicity, including thyrotoxicosis and steatohepatitis, highlighting the need for vigilant monitoring.
Requires monitoring for liver and thyroid dysfunction during amiodarone therapy; leaves open the true incidence in broader populations.
Amiodarone is a highly effective class III antiarrhythmic drug. This drug is an iodine containing compound that tends to accumulate in several organs. With the increasing use of amiodarone, there have been reports of a variety of adverse events to various organs, including the lungs, liver, thyroid gland, eyes, skin, and the nervous system (2). We report a case of Systemic Toxicity of amiodarone involving liver and thyroid.
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Athul et al. (2023) conducted a case report in Amiodarone-induced toxicity (n=1). Amiodarone was evaluated on Development of amiodarone-induced toxicity. Long-term amiodarone therapy in a 77-year-old man caused multi-system toxicity, specifically amiodarone-induced thyrotoxicosis and steatohepatitis.
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