Population
Normal rabbits and rabbits with experimentally produced cardiac hypertrophy, acute myocardial failure, and…
Comparison
Experimentally produced cardiac hypertrophy and… vs Normal rabbits
Design
Preclinical
Authors
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Animal models show differential protein synthesis rates in hypertrophy versus failure but should not guide practice; leaves open human validation needs.
Cardiac hypertrophy increases myocardial protein synthesis, while progression to acute or chronic heart failure diminishes it.
Gudbjarnason et al. (1964) studied this question.
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