Extracorporeal Irradiation of Blood and Lymph in Animals

DESPITE the intensive efforts of many investigators throughout the world only modest and inconstant improvements have been gained in the homotransplantation of tissues and the control of leukemia. The chemotherapeutic and radiotherapeutic maneuvers that aid in the control of immunologic processes and leukemic-cell proliferation also have serious widespread destructive effects upon normal tissues. Not infrequently the sequelae of the destructive effects of these agents upon the bone marrow or the bowel, or both, result in the death of the patient. It has long been believed and now proved that lymphocytic, immunologically competent cells1 are ceaselessly migrating from extravascular sites of . . .