February 1, 1973Acta Physiologica Scandinavica

Circulatory Control via Vagal Afferents: IV. Integration of the central control mechanisms in the circulatory‐adaptation to variations of blood volume

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Population

Sprague-Dawley rats

Design

Preclinical

Authors

JCJan CastenforsStockholm South General Hospital TSTorgny SjöstrandKarolinska University Hospital

Discussion

Member takes

Implication

No immediate clinical implications from rat data; leaves open translation of these afferents to human volume regulation.

Structured PICO

Population

Sprague-Dawley rats

Intervention

Alternative exclusion of afferent discharges via the laryngeal pathway, vagus trunk and sinus nerve, combined with blood infusions, hemorrhage, and carotid occlusion

Outcome

Arterial pressure responsesurrogate

Vagal and laryngeal afferents play a key role in circulatory adaptation to hypervolemia and hypovolemia in a rat model.

Cite This Study

Castenfors et al. (1973) studied this question.

synapsesocial.com/papers/6a86d202713eb98b40ca0dde https://doi.org/10.1111/j.1748-1716.1973.tb05380.x

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Bookmark

Circulatory Control via Vagal Afferents: IV. Integration of the central control mechanisms in the circulatory‐adaptation to variations of blood volume

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Circulatory Control via Vagal Afferents: IV. Integration of the central control mechanisms in the circulatory‐adaptation to variations of blood volume

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider