Key result
Hypertension was associated with higher rates of detectable and elevated hs-TnT compared to normotension, with hs-TnT levels independently related to left ventricular hypertrophy and diastolic function.
Why the study?
Are high-sensitivity troponin T levels associated with left ventricular remodeling and performance in hypertensive subjects?
Observational (n=637)
Are high-sensitivity troponin T levels associated with left ventricular remodeling and performance in hypertensive subjects?
Elevated high-sensitivity troponin T levels may serve as a reliable biomarker for subclinical cardiomyocyte injury and left ventricular remodeling in patients with hypertension.
No takes yet. Share an insight, caveat, or question.
hs-TnT may mark subclinical LV changes in hypertension; hypothesis-generating and should not yet change practice.
Miao et al. (2014) conducted an observational in Hypertension (n=637). Hypertension vs. Normotensive subjects was evaluated on hs-TnT detectable rate (>0.003 ng/mL) and elevated rate (>0.013 ng/mL). Hypertension was associated with higher rates of detectable and elevated hs-TnT compared to normotension, with hs-TnT levels independently related to left ventricular hypertrophy and diastolic function.
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