Why the study?
Does non-invasive coronary flow reserve (CFR) predict left ventricular adverse remodelling after successful primary angioplasty for anterior STEMI?
Population
65 consecutive patients with a first anterior STEMI, after successful primary coronary angioplasty.
Design
Cohort
Follow-up
6 months
Key result
Non-invasive coronary flow reserve <1.7 after successful primary angioplasty for anterior STEMI predicted left ventricular adverse remodeling with 100% sensitivity and 62% specificity (AUC 0.82).
Authors
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May refine post-STEMI remodeling risk stratification; hypothesis-generating pending prospective validation.
Observational (n=65)
Does non-invasive coronary flow reserve (CFR) predict left ventricular adverse remodelling after successful primary angioplasty for anterior STEMI?
Effect estimate: AUC 0.82
p-value: p=<0.001
Non-invasive coronary flow reserve measured within 24 hours of successful primary angioplasty for anterior STEMI is an independent predictor of left ventricular adverse remodeling at 6 months.
Meimoun et al. (2010) conducted an observational in ST-elevation myocardial infarction (STEMI) (n=65). Non-invasive coronary flow reserve (CFR) vs. Higher CFR was evaluated on Left ventricular adverse remodelling (LVR) defined as an absolute increase of ESV ≥15% (AUC 0.82, p=<0.001). Non-invasive coronary flow reserve <1.7 after successful primary angioplasty for anterior STEMI predicted left ventricular adverse remodeling with 100% sensitivity and 62% specificity (AUC 0.82).
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