Key result
Reversal agents and strategies for direct oral anticoagulants are increasingly necessary as these medications rapidly gain popularity over traditional vitamin K antagonists like warfarin.
This review summarizes the strategies and agents used to reverse oral anticoagulants, addressing the growing need due to the increasing popularity of direct oral anticoagulants.
May prompt updated bleeding protocols for DOAC patients; leaves open rigorous trials of reversal efficacy.
For more than half a century, warfarin, a vitamin K antagonist, has been the anticoagulant of choice. However, direct oral anticoagulants are rapidly gaining in popularity, which poses the need for efficacious reversal agents. This review article summarizes the strategies and agents used to reverse oral anticoagulants.
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Griffiths et al. (2017) studied this question. Reversal agents and strategies for direct oral anticoagulants are increasingly necessary as these medications rapidly gain popularity over traditional vitamin K antagonists like warfarin.
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