November 1, 1995The Journal of PhysiologyOpen Access

Dependence of force on length at constant cross‐bridge phosphorylation in the swine carotid media.

View Full Paper

Ask AI

Bookmark

Population

Swine carotid medial ring preparation prepared by removal of the adventitia and endothelium

Design

Preclinical

Authors

CWChristopher J. WingardBellarmine University ABA. BrowneNaples Community Hospital Healthcare System RMRichard A. MurphyUniversity of Southern California

Discussion

Member takes

Implication

Similarity to skeletal muscle supports cross-type mechanics models in swine carotid; leaves open human vascular translation.

Structured PICO

Population

Swine carotid medial ring preparation prepared by removal of the adventitia and endothelium

Intervention

Stretching to various lengths (up to 1.8 L(o)) and stimulation with 100 microM histamine, K(+)-depolarization, or field-stimulation

Outcome

Dependence of force on length and myosin regulatory light chain (MRLC) phosphorylationsurrogate

A swine carotid medial ring preparation allows for the assessment of the descending limb of the force-length relation independently of activation, revealing similarities to vertebrate skeletal muscle.

Cite This Study

Wingard et al. (1995) studied this question.

synapsesocial.com/papers/6a86f21db688e10ffe82baf1 https://doi.org/10.1113/jphysiol.1995.sp021004

View Full Paper

Ask AI

Bookmark

Dependence of force on length at constant cross‐bridge phosphorylation in the swine carotid media.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Dependence of force on length at constant cross‐bridge phosphorylation in the swine carotid media.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider