September 1, 1977AJP Cell Physiology

Mechanical properties of tracheal smooth muscle: effects of temperature

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Population

Isolated canine tracheal smooth muscle (TSM)

Comparison

Temperature variations (37°C, 27°C, 17°C) vs Comparison between different temperatures

Design

Preclinical

Authors

NSN. L. StephensUniversity of Manitoba RCRyan E. CardinalIndiana University Health BSBarbara S. SimmonsUniversity of Washington

Discussion

Member takes

Implication

Warrants caution extrapolating in vitro airway smooth muscle data across temperatures; leaves open relevance to human disease.

Structured PICO

Population

Isolated canine tracheal smooth muscle (TSM)

Intervention

Temperature variations (37°C, 27°C, 17°C)

Comparator

Comparison between different temperatures (37°C, 27°C, 17°C)

Outcome

Isometric tetanic myogram parameters (maximum tetanic tension, contraction time, rate of tension development) and force-velocity relationshipssurrogate

Decreased temperature reduces maximum tetanic tension and alters force-velocity relationships in canine tracheal smooth muscle, likely due to decreased contractile element velocity.

Cite This Study

Stephens et al. (1977) studied this question.

synapsesocial.com/papers/6a86f29b48ef9afcd2a250ba https://doi.org/10.1152/ajpcell.1977.233.3.c92

View Full Paper

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Mechanical properties of tracheal smooth muscle: effects of temperature

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Mechanical properties of tracheal smooth muscle: effects of temperature

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider