August 1, 1986AJP Heart and Circulatory Physiology
In vivo mechanical behavior of canine pericardium
Population
13 open-chest dogs (10 for main experiment, 3 for in situ arrested heart preparation)
Design
Preclinical
Authors
Discussion
Loading...
Member takes
Implication
Pericardial strain is predominantly circumferential in canines; leaves open relevance to human pericardial constraint or effusion physiology.
Structured PICO
P
Population
13 open-chest dogs (10 for main experiment, 3 for in situ arrested heart preparation)
I
Intervention
Alteration of venous return (caval occlusion followed by volume loading), severing of pericardial diaphragmatic attachments, and saline infusion
O
Outcome
In vivo mechanical behavior of the pericardium (circumferential and longitudinal strain)surrogate
The canine pericardium exhibits marked directional variability in lengthening, stretching primarily in the circumferential direction when internal volume increases.
Cite This Study
Mann et al. (1986) studied this question.