What does this research mean for the field?

Q: What does this research mean for the field?

Pericardial surface pressure is nonuniform, exhibiting significant local differences over the lateral ventricular surfaces during acute changes in afterload. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

June 1, 1987Circulation

Nonuniformity of pericardial surface pressure in dogs.

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Why the study?

Do acute changes in afterload cause nonuniform changes in pericardial surface pressure in dogs?

Population

11 anesthetized dogs instrumented to measure ventricular dimensions and pressure, with pericardial balloons…

Design

Preclinical

Authors

OSOtto A. SmisethOslo University Hospital NSNairne Scott‐DouglasUniversity of Calgary CTChristopher ThompsonGeneral Cardiology

Discussion

Member takes

Implication

Regional pericardial effects warrant consideration in ventricular interaction models; leaves open human translation.

Structured PICO

Do acute changes in afterload cause nonuniform changes in pericardial surface pressure in dogs?

Population

11 anesthetized dogs instrumented to measure ventricular dimensions and pressure, with pericardial balloons placed over the right and left ventricular free walls

Intervention

Transient constrictions of the ascending aorta and pulmonary artery, and angiotensin infusion before and after intravenous saline infusion

Outcome

Pericardial pressure over the right and left ventricular free wallssurrogate

There are significant local differences in pericardial pressure over the lateral ventricular surfaces during acute changes in afterload in a canine model.

Cite This Study

Smiseth et al. (1987) studied this question.

synapsesocial.com/papers/6a1bf4856f692abb725efd9e https://doi.org/10.1161/01.cir.75.6.1229

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June 1, 1987Circulation

Nonuniformity of pericardial surface pressure in dogs.

View Full Paper

Ask AI

Bookmark

Why the study?

Do acute changes in afterload cause nonuniform changes in pericardial surface pressure in dogs?

Population

11 anesthetized dogs instrumented to measure ventricular dimensions and pressure, with pericardial balloons…

Design

Preclinical

Authors

OSOtto A. SmisethOslo University Hospital NSNairne Scott‐DouglasUniversity of Calgary CTChristopher ThompsonGeneral Cardiology

Discussion

Member takes

Implication

Regional pericardial effects warrant consideration in ventricular interaction models; leaves open human translation.

Structured PICO

Do acute changes in afterload cause nonuniform changes in pericardial surface pressure in dogs?

Population

11 anesthetized dogs instrumented to measure ventricular dimensions and pressure, with pericardial balloons placed over the right and left ventricular free walls

Intervention

Transient constrictions of the ascending aorta and pulmonary artery, and angiotensin infusion before and after intravenous saline infusion

Outcome

Pericardial pressure over the right and left ventricular free wallssurrogate

There are significant local differences in pericardial pressure over the lateral ventricular surfaces during acute changes in afterload in a canine model.

Cite This Study

Smiseth et al. (1987) studied this question.

synapsesocial.com/papers/6a1bf4856f692abb725efd9e https://doi.org/10.1161/01.cir.75.6.1229

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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