Population
Human muscle biopsies from normal adults, human fetal and neonatal muscle, and patients with Duchenne's…
Comparison
Immunofluorescence using an antibody raised… vs Normal adult muscle
Design
Preclinical
Authors
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May aid regeneration assessment in DMD biopsies; hypothesis-generating for diagnostics, pending validation.
Fetal myosin immunoreactivity in Duchenne's dystrophy reflects the reexpression of fetal-specific myosin isoforms, providing a tool for identifying regenerating fibers.
Schiaffino et al. (1986) studied this question.
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