Why the study?
Does oral sodium diphenylhydantoin improve rhythm control in symptomatic patients with recurrent cardiac arrhythmias resistant to conventional therapy?
Population
60 symptomatic patients with recurrent cardiac arrhythmias resistant to conventional antiarrhythmic therapy.
Design
Case_series
Follow-up
average of 16.8 months
Authors
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May support phenytoin consideration in refractory arrhythmias; hypothesis-generating and should not change practice without RCTs.
Does oral sodium diphenylhydantoin improve rhythm control in symptomatic patients with recurrent cardiac arrhythmias resistant to conventional therapy?
Oral sodium diphenylhydantoin demonstrated efficacy in maintaining sinus rhythm or reducing arrhythmia frequency in a majority of patients with refractory recurrent cardiac arrhythmias.
H Bernstein (1965) studied this question.
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