Why the study?
Does exercise-induced mitral regurgitation limit stroke volume adaptation and exercise capacity in patients with left ventricular systolic dysfunction?
Population
25 heart failure patients with left ventricular systolic dysfunction, mean age 53+/-12 years.
Design
Cross-sectional
Authors
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Exercise-induced MR may limit exercise capacity in LV systolic dysfunction; hypothesis-generating for targeted interventions.
Does exercise-induced mitral regurgitation limit stroke volume adaptation and exercise capacity in patients with left ventricular systolic dysfunction?
In patients with left ventricular dysfunction, exercise-induced worsening of functional mitral regurgitation limits stroke volume adaptation and exercise capacity.
Lapu-Bula et al. (2002) studied this question.
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