January 1, 1988Nucleic Acids ResearchOpen Access

Human Ul snRNP-specificC protein: complete cDNA and protein sequence and identification of a multigene family in mammals

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Population

Human teratocarcinoma cDNA library, HeLa cells, and genomic DNA from various vertebrate species

Design

Preclinical

Authors

PSPeter SillekensBiocartis (Belgium)RBRia P. BeijerRadboud University Nijmegen WHWinand J. HabetsRadboud University Nijmegen

Discussion

Member takes

Implication

Provides foundational sequence data for splicing research; leaves open any clinical or therapeutic implications pending functional studies.

Structured PICO

Population

Human teratocarcinoma cDNA library, HeLa cells, and genomic DNA from various vertebrate species (Drosophila, Tilapia, Xenopus, Varan, chicken, duck, rabbit, rat, mouse, hamster, mole, mole rat, calf, monkey, man)

Intervention

Cloning, sequencing, and in vitro translation of human U1 snRNP-specific C protein cDNA

Outcome

Nucleotide sequence of the 733 bp cDNA insert and deduced 159 amino acid sequence of the U1 snRNP-specific C protein

The study provides the complete cDNA and deduced amino acid sequence of the human U1 snRNP-specific C protein, revealing it is post-translationally modified and encoded by a multigene family in mammals.

Cite This Study

Sillekens et al. (1988) studied this question.

synapsesocial.com/papers/6a87134b36c36f97809ed35d https://doi.org/10.1093/nar/16.17.8307

View Full Paper

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Implication

Provides foundational sequence data for splicing research; leaves open any clinical or therapeutic implications pending functional studies.

Human Ul snRNP-specificC protein: complete cDNA and protein sequence and identification of a multigene family in mammals

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Human Ul snRNP-specificC protein: complete cDNA and protein sequence and identification of a multigene family in mammals

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider