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July 27, 2011BMC GastroenterologyOpen Access

Laparoscopic-assisted surgery for non-metastatic colorectal cancer significantly improved postoperative recovery times and shortened hospital stays compared to open surgery, with no significant differences in medium-term recurrence or overall survival.

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Why the study?

Does laparoscopic-assisted surgery improve perioperative recovery and maintain similar medium-term survival and recurrence rates compared to open surgery in patients with non-metastatic colorectal cancer?

Population

519 patients with non-metastatic colorectal cancer treated at a single center in China.

Comparison

Laparoscopic-assisted surgery for colorectal… vs Open surgery (OP) for colorectal cancer

Design

Case-control, None

Follow-up

Median 37.1 months for LAP and 36.7 months for OP

Key result

Laparoscopic-assisted surgery for non-metastatic colorectal cancer significantly improved postoperative recovery times and shortened hospital stays compared to open surgery, with no significant differences in medium-term recurrence or overall survival.

Authors

JSJing SunTJTao JiangZQZhengjun Qiu

Discussion

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Member takes

Overview

May support faster recovery with laparoscopic-assisted surgery; leaves open need for RCTs to confirm oncological equivalence.

Study Design

Type

Case-Control (n=519)

Multicenter

No

Structured PICO

Does laparoscopic-assisted surgery improve perioperative recovery and maintain similar medium-term survival and recurrence rates compared to open surgery in patients with non-metastatic colorectal cancer?

P
Population
519 patients with non-metastatic colorectal cancer who underwent either laparoscopic-assisted or open surgery, followed for a median of approximately 37 months.
I
Intervention
Laparoscopic-assisted surgery (LAP) for colorectal cancer
C
Comparator
Open surgery (OP) for colorectal cancer
O
Outcome
Short-term perioperative outcomes (recovery, complications) and medium-term recurrence and overall survivalhard clinical

Main Result

Absolute Event Rate: 21.4% vs 28%

p-value: p=0.113

Laparoscopic-assisted surgery for non-metastatic colorectal cancer provides faster postoperative recovery with equivalent medium-term oncological outcomes compared to open surgery.

Limitations

  • Retrospective case-control design with partial randomization based on target dates and theatre availability.
  • Learning curve bias, as all anastomotic leakages in the laparoscopic group occurred in early cases.
  • Single-center study, which may limit generalizability.

Cite This Study

Sun et al. (2011) conducted a case-control in Non-metastatic colorectal cancer (n=519). Laparoscopic-assisted surgery vs. Open surgery was evaluated on Overall mortality (colon cancer cases) (p=0.113). Laparoscopic-assisted surgery for non-metastatic colorectal cancer significantly improved postoperative recovery times and shortened hospital stays compared to open surgery, with no significant differences in medium-term recurrence or overall survival.

synapsesocial.com/papers/6a8713bc37e82e140d15464ehttps://doi.org/10.1186/1471-230x-11-85
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Also Consider

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  1. 1Comparison of open and laparoscopic surgical techniques in colorectal cancer surgery: Early and late results2026
  2. 2Colorectal Surgery: Single Tertiary Center Experience2023 · 1 citations
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  4. 4Comparative Outcomes of Open Versus Laparoscopic Colon Surgery: A Propensity Score-Matched Analysis of Postoperative Complications, Recovery Times, and Long-Term Survival2025
  5. 5A Meta-Analysis of the Short- and Long-Term Results of Randomized Controlled Trials That Compared Laparoscopy-Assisted and Conventional Open Surgery for Colorectal Cancer2011 · 83 citations