Key result
A patient with primary hepatic angiosarcoma survived 14 years without further recurrence following an initial right hemihepatectomy, a subsequent segmentectomy, and adjuvant radiotherapy.
Why the study?
Primary hepatic angiosarcomas are rare, aggressive liver malignancies with poor outcomes and management challenges, though early diagnosis, aggressive resection, and surveillance can confer prolonged survival.
Case Report (n=1)
Early diagnosis, aggressive surgical resection, ongoing surveillance, and adjuvant radiotherapy can confer prolonged survival in primary hepatic angiosarcoma.
May support extended PHA survival with resection and surveillance; leaves open prospective validation of optimal strategies.
Primary hepatic angiosarcomas (PHAs) are rare primary liver malignancies with poor outcomes due to their aggressive nature and the difficulty it presents in terms of diagnosis and management. However, early diagnosis and aggressive surgical resection combined with ongoing surveillance can confer prolonged survival in patients with PHA. Additionally, adjuvant radiotherapy may be of benefit in cases of involved surgical margins. Here we report the longest surviving patient with PHA in literature to date. The patient had an initial right hemihepatectomy 14 years ago and 10 years later had a segment III segmentectomy for recurrence on surveillance imaging. This was followed with adjuvant radiotherapy for involved margins. There has been no further recurrence noted on imaging to date, and the patient is continuing to thrive in the community.
No takes yet. Share an insight, caveat, or question.
Chen et al. (2022) conducted a case report in Primary hepatic angiosarcoma (n=1). Surgical resection and adjuvant radiotherapy was evaluated on Survival and recurrence. A patient with primary hepatic angiosarcoma survived 14 years without further recurrence following an initial right hemihepatectomy, a subsequent segmentectomy, and adjuvant radiotherapy.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: