Key result
A patient presenting with jaundice, elevated liver enzymes, and infiltrative liver masses was diagnosed with primary hepatic angiosarcoma via biopsy.
Why the study?
Primary hepatic angiosarcoma is a rare, aggressive liver tumor with poor prognosis, limited treatment options, and no typical clinical presentation.
Case Report (n=1)
Primary hepatic angiosarcoma should be considered in the differential diagnosis for patients presenting with an infiltrative liver mass.
Case illustrates PHA mimicking cirrhosis; hypothesis-generating for biopsy timing in jaundiced patients with lesions.
Primary hepatic angiosarcoma (PHA) is a rare and aggressive mesenchymal liver tumor with a poor prognosis and high mortality. Treatment options are limited to palliative chemotherapy with surgical resection reserved for the few cases that present early. We present a case of a patient who presented with jaundice and elevated liver enzymes. Imaging identified a diffusely heterogeneous liver consistent with cirrhosis, findings of portal hypertension, and 2 ill-defined liver lesions. Biopsy results confirmed PHA. Primary hepatic angiosarcoma does not have a typical presentation but should be considered for any patient presenting with an infiltrative liver mass.
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Shaaban et al. (2022) conducted a case report in Primary hepatic angiosarcoma (n=1). A patient presenting with jaundice, elevated liver enzymes, and infiltrative liver masses was diagnosed with primary hepatic angiosarcoma via biopsy.
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