Key result
CT angiography, MRI, and surgical biopsy confirm primary hepatic angiosarcoma over suspected hepatic AVMs.
Why the study?
Primary hepatic angiosarcoma is a rare and aggressive malignancy with nonspecific symptoms and varied imaging presentations, making early diagnosis challenging.
Case Report (n=1)
This case highlights the diagnostic challenges of primary hepatic angiosarcoma due to its varied imaging presentations.
Raises suspicion for PHA in hemoperitoneum initially attributed to AVM; leaves open optimal diagnostic algorithms for rare hepatic tumors.
Primary hepatic angiosarcoma (PHA) is a rare and aggressive malignancy, accounting for roughly 2% of primary hepatic cancers. It is characterized by rapid progression and nonspecific clinical symptoms, making early diagnosis challenging. This case report describes a 59-year-old male who initially presented with right upper quadrant (RUQ) pain, dizziness, and presyncope, with initial imaging findings suggesting hemoperitoneum secondary to hepatic arteriovenous malformations (AVM). A comprehensive diagnostic approach, including computed tomography (CT) angiography, magnetic resonance imaging (MRI), and surgical biopsy, ultimately confirmed PHA. This case underscores the difficulty in diagnosing PHA due to its varied imaging presentations and highlights the need for improved diagnostic strategies and early detection.
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Crawford et al. (2025) conducted a case report in Primary hepatic angiosarcoma (n=1). Diagnostic approach (CT angiography, MRI, and surgical biopsy) was evaluated on Diagnosis of primary hepatic angiosarcoma. A comprehensive diagnostic approach including CT angiography, MRI, and surgical biopsy successfully confirmed primary hepatic angiosarcoma in a patient initially suspected of having hepatic AVMs.
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