Why the study?
Does ceforanide reduce postoperative infections compared to cephalothin in patients undergoing cardiovascular surgery?
Population
220 patients undergoing cardiovascular surgery, including a subgroup of 165 patients undergoing only…
Comparison
Ceforanide as perioperative antibiotic… vs Cephalothin as perioperative antibiotic…
Design
RCT, Randomly assigned
Authors
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Supports ceforanide over cephalothin for CABG prophylaxis; extends RCT evidence on optimal perioperative antibiotics.
Does ceforanide reduce postoperative infections compared to cephalothin in patients undergoing cardiovascular surgery?
Ceforanide is superior to cephalothin as perioperative antibiotic prophylaxis for preventing infections after coronary artery bypass surgery.
Richard Platt (1984) studied this question.
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