Why the study?
Does the prevalence of the Brugada sign differ between patients with idiopathic ventricular fibrillation and healthy controls?
Population
39 consecutive patients with idiopathic ventricular fibrillation and 592 age-matched healthy controls.
Comparison
ECG evaluation for the presence of Brugada sign vs Healthy controls
Design
Case-control, Four investigators blinded to the subjects' status
Authors
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Definite Brugada sign may flag arrhythmic risk in idiopathic VF; supports diagnostic specificity but leaves open prospective validation.
Does the prevalence of the Brugada sign differ between patients with idiopathic ventricular fibrillation and healthy controls?
A definite Brugada sign is highly specific for arrhythmic risk in idiopathic VF, while questionable signs are seen in healthy controls and lack diagnostic value.
Sami Viskin (2000) studied this question.
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