Apparent induction of ventricular tachycardia after “appropriate pacing” by an implantable dual chamber defibrillator: confusing ICD electrograms

Q: What is the clinical evidence from this study?

Study design: Case-Control. Population: Idiopathic ventricular fibrillation (n=631). Intervention: Idiopathic ventricular fibrillation vs. Healthy controls. Primary outcome: Definite Brugada sign (p=< 0.005).

Q: What does this research mean for the field?

A definite Brugada sign occurs in 21% of patients with idiopathic ventricular fibrillation compared to 0% of healthy controls, serving as a specific marker of arrhythmic risk. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Dominic A.M.J. Theuns; Luc J.L.M. Jordaens

doi:10.1136/heart.84.1.36

July 1, 2000HeartOpen Access

Apparent induction of ventricular tachycardia after “appropriate pacing” by an implantable dual chamber defibrillator: confusing ICD electrograms

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Why the study?

The prevalence and diagnostic specificity of the Brugada sign in idiopathic ventricular fibrillation compared to healthy individuals was unclear.

Study Design

Type

Case-Control (n=631)

Blinding

Blinded

PICO

P

Population

631 participants, including 39 consecutive patients with idiopathic ventricular fibrillation and 592 age-matched healthy controls.

E

Exposure / Comparator

Idiopathic ventricular fibrillation vs Healthy controls

O

Primary Outcome

Definite Brugada sign, p=< 0.005

Main Result

Absolute Event Rate: 21% vs 0%

p-value: p=< 0.005

Abstract

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Discussion

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Cite This Study

Theuns et al. (2000) conducted a case-control in Idiopathic ventricular fibrillation (n=631). Idiopathic ventricular fibrillation vs. Healthy controls was evaluated on Definite Brugada sign (p=< 0.005).

synapsesocial.com/papers/6ac47e3deb6b1a93995a7368 https://doi.org/10.1136/heart.84.1.36

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Apparent induction of ventricular tachycardia after “appropriate pacing” by an implantable dual chamber defibrillator: confusing ICD electrograms

Study Design

PICO

Main Result

Abstract

Discussion

Cite This Study

Apparent induction of ventricular tachycardia after “appropriate pacing” by an implantable dual chamber defibrillator: confusing ICD electrograms

Study Design

PICO

Main Result

Abstract

Discussion

Cite This Study

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