Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
February 27, 1969New England Journal of Medicine

Platelet Dysfunction — Differentiation of a Newly Recognized Primary Type from That Produced by Aspirin

View Full Paper
Ask AI
Bookmark
Share

Population

Patients with a recently described hemorrhagic disorder characterized by defective platelet aggregation…

Design

Other

Authors

MSMervyn A. SahudQuest Diagnostics (United States)PAPaul M. AggelerSanta Clara Valley Medical Center

Discussion

Loading...

Member takes

Implication

Distinguishes primary platelet dysfunction from aspirin effects in bleeding patients; hypothesis-generating for targeted testing pending larger validation studies.

Structured PICO

P
Population
Patients with a recently described hemorrhagic disorder characterized by defective platelet aggregation induced by collagen and epinephrine
C
Comparator
Aspirin-induced platelet defect
O
Outcome
Platelet aggregation and adhesion characteristicssurrogate

This study differentiates a primary hemorrhagic disorder of platelet dysfunction from aspirin-induced defects based on distinct aggregation and adhesion profiles.

Cite This Study

Sahud et al. (1969) studied this question.

synapsesocial.com/papers/6a8735573a1d8ec5fdd3e673https://doi.org/10.1056/nejm196902272800901
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Release of a Platelet-Aggregating Substance (Adenosine Diphosphate) from Rabbit Blood Platelets Induced by Saline “Extract” of Tendons1963 · 181 citations
  2. 2The Stuart-Prower Factor Assay and its Clinical Significance1958 · 232 citations
  3. 3Blood Coagulation, Hemorrhage and Thrombosis: Methods of Study1965 · 21 citations