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This review outlines the physiological and pathophysiological mechanisms governing pulmonary blood flow, emphasizing endothelial function and hemodynamic responses to pressure changes and ischemia.
In the review the mechanisms of the pulmonary blood flow regulation in the normal conditions and experimental pathology are discussed. The modern information, concerned neurohumoral and biophysical regulatory mechanisms of the pulmonary vessels is represented. The role of the endothelial cells in the active pulmonary vessels dilatation following increasing of the pulmonary flow is stressed. The hemodynamics mechanisms of the pulmonary artery pressure and flow changes following pressor and depressor arterial pressure shifts and myocardial ischemia are summarized.
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Евлахов et al. (2013) studied this question.
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