Key result
Mapping with the magnetic-based LASSOSTAR NAV catheter during cryoballoon ablation for AF produced comparable LA geometry to Pentaray, with similar low voltage area detection (13.9% vs 18.3%, p=0.07).
Why the study?
Current cryoballoon circular catheters are sensed only by impedance-based mapping systems, limiting map accuracy, prompting investigation of a magnetic-based circular mapping catheter.
Does a magnetic-based circular mapping catheter (LASSOSTAR NAV) provide comparable left atrial mapping accuracy to a high-density mapping catheter (Pentaray) during cryoballoon ablation for atrial fibrillation?
Observational (n=19)
Does a magnetic-based circular mapping catheter (LASSOSTAR NAV) provide comparable left atrial mapping accuracy to a high-density mapping catheter (Pentaray) during cryoballoon ablation for atrial fibrillation?
The magnetic-based circular LASSOSTAR NAV catheter is safe and effective for guiding cryoballoon PVI, providing accurate left atrial geometry comparable to high-density mapping.
Answers are grounded in this paper and cite their sources.
Supports LASSOSTAR NAV for LA mapping in cryoballoon AF ablation; leaves open low-voltage equivalence pending larger validation studies.
INTRODUCTION: The circular catheter compatible with current cryoballoon system for atrial fibrillation (AF) ablation is exclusively sensed by impedance-based electro-anatomical mapping (EAM) system, limiting the accuracy of maps. We aim to investigate the feasibility and safety of a magnetic-based circular mapping catheter for AF ablation with cryoballoon. METHODS: Nineteen consecutive patients who underwent pulmonary vein isolation (PVI) with cryoballoon for paroxysmal or persistent AF were included. EAMs of left atrium (LA) created by the LASSOSTAR™NAV catheter (Lassostar map) before and after PVI were compared to that generated by a high-density mapping catheter (Pentaray map) from different aspects including structural similarity, PV angle, LA posterior wall (LAPW) and low voltage areas (LVAs), and the amplitude of far field electrograms (FFEs) recorded by catheters. RESULTS: All patients had successful PVI without major complications. With similar mapping time and density, the LA volume calculated from the Pentaray map and Lassostar map were comparable. There were no significant differences in PV angle of all PVs and PW area (16.8 ± 3.2 vs. 17.1 ± 2.8, p = .516) between Pentaray map and Lassostar map. High structural similarity score was observed between two maps (0.783 in RAO/LAO view and 0.791 in PA view). Lassostar map detected lesser but not statistically significant extension of LVA (13.9% vs. 18.3%, p = .07). Amplitude of FFE was larger at the right superior PV on Lassostar map (0.21 ± 0.16 vs. 0.14 ± 0.11 mV, p = .041) compared to that on the Pentaray map. CONCLUSION: In our initial experience, PVI with cryoballoon and magnetic-based circular LASSOSTAR™NAV catheter was safe and effective based on the accurate LA geometry it created.
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Liao et al. (2023) conducted an observational in Paroxysmal or persistent atrial fibrillation (n=19). Magnetic-based circular mapping catheter (LASSOSTAR™NAV) vs. High-density mapping catheter (Pentaray) was evaluated on Low voltage area (LVA) extension (p=0.07). Mapping with the magnetic-based LASSOSTAR NAV catheter during cryoballoon ablation for AF produced comparable LA geometry to Pentaray, with similar low voltage area detection (13.9% vs 18.3%, p=0.07).
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