Why the study?
Do left ventricular mechanoenergetics directly reflect changes in mitochondrial energetics in different types of acute failing canine hearts?
Population
Canine excised cross-circulated hearts with induced acute failure
Comparison
Induction of three different types of acute… vs Comparison among the three different types of…
Design
Preclinical
Authors
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LV mechanoenergetics do not mirror mitochondrial changes across acute HF etiologies; leaves open etiology-specific mitochondrial targeting.
Do left ventricular mechanoenergetics directly reflect changes in mitochondrial energetics in different types of acute failing canine hearts?
In a canine model of acute heart failure, left ventricular mechanoenergetics do not directly reflect changes in mitochondrial energetics, which vary depending on the etiology of failure.
Zhao et al. (1995) studied this question.
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