Key result
The provided text is a journal masthead and contains no clinical study data.
Population
Male Sprague-Dawley rats
Comparison
Transverse aortic constriction for 20 weeks to… vs Control rats (implied by comparative statistics)
Design
Preclinical
Follow-up
20 weeks
Authors
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Selective interfibrillar mitochondrial impairment may underlie contractile dysfunction in pressure-overload HF; hypothesis-generating and should not change practice.
Contractile dysfunction in pressure overload-induced heart failure is associated with selective impairment of respiratory capacity in interfibrillar mitochondria, supporting their primary role in providing ATP for contractile function.
Schwarzer et al. (2009) studied this question. The provided text is a journal masthead and contains no clinical study data.
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