Key result
The provided text is a journal masthead and contains no clinical study data.
Population
Male Sprague-Dawley rats
Comparison
Transverse aortic constriction for 10 or 20… vs Control animals
Design
Preclinical
Follow-up
10 or 20 weeks
Authors
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Insulin resistance may precede HF in pressure overload; leaves open whether targeting it alters clinical outcomes.
In a rat model of pressure overload, insulin resistance precedes the onset of mitochondrial and contractile dysfunction, suggesting a potential mechanistic role in the development of heart failure.
Schwarzer et al. (2009) studied this question. The provided text is a journal masthead and contains no clinical study data.
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