Why the study?
Does enflurane general anesthesia alter plasma levels of thyroid hormones during surgery?
Population
Patients undergoing surgery receiving general anesthesia (specific demographics and sample size not reported)
Comparison
General anesthesia (specifically enflurane) vs Preanesthesia levels (baseline)
Design
Other
Follow-up
Postoperatively
Authors
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May warrant thyroid monitoring with enflurane anesthesia; leaves open clinical impact and relevance to modern agents.
Does enflurane general anesthesia alter plasma levels of thyroid hormones during surgery?
Enflurane anesthesia causes a transient intraoperative increase in free and total thyroxine levels, likely due to intercompartmental shifting rather than increased TSH secretion.
Börner et al. (1995) studied this question.
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