Why the study?
Does general anesthesia with enflurane affect plasma levels of thyroid hormones during surgery?
Population
Patients undergoing surgery
Comparison
Different types of general anesthesia vs Preanesthesia levels
Design
Other
Follow-up
Intraoperative and postoperative
Authors
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May warrant caution interpreting thyroid labs under enflurane; leaves open clinical relevance and applicability to current anesthetics.
Does general anesthesia with enflurane affect plasma levels of thyroid hormones during surgery?
Enflurane anesthesia causes a transient intraoperative increase in plasma fT4 and tT4 levels, likely due to hormone release or intercompartmental shifting rather than increased TSH secretion.
Börner et al. (1995) studied this question.
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